BDBM50067239 CHEMBL555556::N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-cyano-phenyl)-ureido]-N-methyl-acetamide; hydrochloride

SMILES CN(C(=O)CNC(=O)Nc1cccc(c1)C#N)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl

InChI Key InChIKey=PPTGAAIAJSLPKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067239   

TargetB2 bradykinin receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067239(N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-ylo...)
Affinity DataIC50: 1.40nMAssay Description:Concentration required to inhibit specific binding of [3H]BK at 0.06 nM to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067239(N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-ylo...)
Affinity DataIC50: 1.40nMAssay Description:Concentration required to inhibit specific binding of [3H]BK at 0.06 nM to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed