BDBM50066683 (S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-2-hydroxysuccinic acid::(S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl]-2-hydroxy-succinic acid::CHEMBL119628

SMILES O[C@H](CCCCCCc1ccc(Cl)cc1Cl)C[C@](O)(CC(O)=O)C(O)=O

InChI Key InChIKey=NPZOIISFQXTCQN-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50066683   

TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity was tested against rat ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity was tested against rat ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  770nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  770nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity was tested against human recombinant ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ATP citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of rat ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed