BDBM50066612 (E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-one::2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylidene]-1-cycloheptanone::CHEMBL326552

SMILES NC(=N)c1cccc(\C=C2/CCCC\C(=C/c3cccc(c3)C(N)=N)C2=O)c1

InChI Key InChIKey=PHAIUFIPJBFOPT-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066612   

TargetSerine protease 1(Bovine)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066612(2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylid...)
Affinity DataKi:  410nMAssay Description:In vitro inhibition of bovine trypsin(Trp).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066612(2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylid...)
Affinity DataKi:  410nMAssay Description:Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066612(2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylid...)
Affinity DataKi:  1.40E+3nMAssay Description:Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066612(2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylid...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibition of human coagulation factor Xa (Xa) in a purified enzyme system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066612(2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylid...)
Affinity DataKi:  2.10E+3nMAssay Description:Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066612(2,7-di[1-[3-amino(imino)methylphenyl]-(E)-methylid...)
Affinity DataKi:  2.10E+3nMAssay Description:In vitro inhibition of human thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed