BDBM50066441 2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione::2-(2,6-dimethylphenyl)isoindoline-1,3-dione::CHEMBL8916

SMILES Cc1cccc(C)c1N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=KDCNGAZTEPFIKL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066441   

TargetDipeptidyl peptidase 4(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: 3.97E+5nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: 3.97E+5nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed