BDBM50066318 CHEMBL108888::N'-(2-fluorobenzoyl)-2-naphthohydrazide::Naphthalene-2-carboxylic acid N'-(2-fluoro-benzoyl)-hydrazide

SMILES Fc1ccccc1C(=O)NNC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=BHGKYYRQGUSTGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066318   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066318(N'-(2-fluorobenzoyl)-2-naphthohydrazide | Naphthal...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066318(N'-(2-fluorobenzoyl)-2-naphthohydrazide | Naphthal...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50066318(N'-(2-fluorobenzoyl)-2-naphthohydrazide | Naphthal...)
Affinity DataIC50: 400nMAssay Description:Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed