BDBM50066303 2-(2-Hydroxy-benzoyl)-4-[1-(3-hydroxy-phenyl)-meth-(E)-ylidene]-5-methyl-2,4-dihydro-pyrazol-3-one::CHEMBL285489::CHEMBL412570

SMILES Oc1cccc(C=c2c(=C)[nH]n(C(=O)c3ccccc3O)c2=O)c1

InChI Key InChIKey=AWJKUBDNKSTCNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066303   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066303(CHEMBL285489 | CHEMBL412570 | 2-(2-Hydroxy-benzoyl...)
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066303(CHEMBL285489 | CHEMBL412570 | 2-(2-Hydroxy-benzoyl...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066303(CHEMBL285489 | CHEMBL412570 | 2-(2-Hydroxy-benzoyl...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed