BDBM50066300 (4Z)-2-(4-chlorobenzoyl)-4-[(4- hydroxyphenyl)methylidene]-5-methylpyrazol-3-one (Compound 16)::2-(4-Chloro-benzoyl)-4-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-5-methyl-2,4-dihydro-pyrazol-3-one::CHEMBL107777::CHEMBL441600

SMILES Oc1ccc(C=c2c(=C)[nH]n(C(=O)c3ccc(Cl)cc3)c2=O)cc1

InChI Key InChIKey=GLKKMTAPUFNFGI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066300   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Nirma University

LigandPNGBDBM50066300(CHEMBL441600 | (4Z)-2-(4-chlorobenzoyl)-4-[(4- hyd...)
Affinity DataIC50: 2.93E+5nMAssay Description:HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2014
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066300(CHEMBL441600 | (4Z)-2-(4-chlorobenzoyl)-4-[(4- hyd...)
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066300(CHEMBL441600 | (4Z)-2-(4-chlorobenzoyl)-4-[(4- hyd...)
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066300(CHEMBL441600 | (4Z)-2-(4-chlorobenzoyl)-4-[(4- hyd...)
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed