BDBM50066235 CHEMBL3400449

SMILES COCCCOc1cc(ccc1OC)C(=O)N(C[C@@H]1CNC[C@H]1NC(=O)OCC1CCCCC1)C(C)C

InChI Key InChIKey=HLXHCRZAVCFDIS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066235   

TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066235(CHEMBL3400449)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human renin by fluorescence based FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066235(CHEMBL3400449)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human renin by fluorescence based FRET assay in presence of plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066235(CHEMBL3400449)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using DBF fluorometric substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50066235(CHEMBL3400449)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam fluorometric substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed