BDBM50066136 CHEMBL3400291

SMILES CN(C)C(=O)Oc1ccc2c(C)c(Cc3cccc(c3)N(C)S(=O)(=O)CCCNCCCCCC(=O)N3CCN(CC3)c3nc(nc(n3)-n3c(nc4ccccc34)C(F)F)N3CCOCC3)c(=O)oc2c1

InChI Key InChIKey=KYJAPJCTKKWSCJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066136   

TargetAurora kinase B(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50066136(CHEMBL3400291)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AurB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50066136(CHEMBL3400291)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKC-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50066136(CHEMBL3400291)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50066136(CHEMBL3400291)
Affinity DataIC50: 473nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50066136(CHEMBL3400291)
Affinity DataIC50: 172nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
The University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50066136(CHEMBL3400291)
Affinity DataIC50: 473nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed