BDBM50065941 1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine::CHEMBL28211

SMILES COc1ccc2C(=C(CCc2c1)c1ccccc1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=JEYWNNAZDLFBFF-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50065941   

TargetAndrogen receptor(Rat)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)
Affinity DataIC50: 41nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)
Affinity DataKi:  0.900nMAssay Description:Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)
Affinity DataKi:  30nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetC-8 sterol isomerase ERG2(Baker's yeast)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)
Affinity DataKi:  232nMAssay Description:Affinity for ERG2 of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed