BDBM50065843 CHEMBL553081::CHEMBL555715::N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine

SMILES NCc1cccc(c1)N=C(N)c1cccs1

InChI Key InChIKey=FODVLWUSSFCSRG-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50065843   

TargetNitric oxide synthase, brain(Rat)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50065843(CHEMBL555715 | CHEMBL553081 | N-(3-Aminomethyl-phe...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50065843(CHEMBL555715 | CHEMBL553081 | N-(3-Aminomethyl-phe...)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50065843(CHEMBL555715 | CHEMBL553081 | N-(3-Aminomethyl-phe...)
Affinity DataKi:  8.70nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS) isoenzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50065843(CHEMBL555715 | CHEMBL553081 | N-(3-Aminomethyl-phe...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS) isoenzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50065843(CHEMBL555715 | CHEMBL553081 | N-(3-Aminomethyl-phe...)
Affinity DataKi:  400nMAssay Description:Inhibitory activity against human endothelial nitric oxide synthase (eNOS) isoenzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed