BDBM50065796 (E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-carboxylic acid::2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-carboxylic acid::2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::2-[2-((E)-3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::CHEMBL39092

SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O

InChI Key InChIKey=XQDVWYSATRRSMJ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50065796   

TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro anti-HIV integrase activity against integration (strand transfer) of target plasmid.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.40E+3nMAssay Description:HIV integrase inhibitory potency was evaluated as IC50 on 3' processing of target DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Unité

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory concentration against HIV-1 recombinant integrase activity in standard 3'-processing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Unité

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against HIV-1 recombinant integrase activity in strand transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGag-Pol polyprotein(RSV-Pr-C)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of rous sarcoma virus (RSV) Integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed