BDBM50065793 8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl]-quinoline-7-carboxylic acid::8-Hydroxy-2-[2-(3,4,5-trihydroxy-phenyl)-vinyl]-quinoline-7-carboxylic acid::8-hydroxy-2-(3,4,5-trihydroxystyryl)quinoline-7-carboxylic acid::CHEMBL37869

SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O

InChI Key InChIKey=DEHWDDWRZXNDCL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50065793   

TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 300nMAssay Description:HIV integrase inhibitory potency was evaluated as IC50 on 3' processing of target DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 400nMAssay Description:In vitro anti-HIV integrase activity against integration (strand transfer) of target plasmid.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein(RSV-Pr-C)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rous sarcoma virus (RSV) Integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed