BDBM50065688 CHEMBL3404008

SMILES COc1ccc(Cn2c3nc(ncc3c(cc2=O)-c2ccccn2)N2CCC[C@H]2CO)cc1Cl

InChI Key InChIKey=MKENMLADARUDLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065688   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50065688(CHEMBL3404008)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP incubated for 30 mins by scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed