BDBM50065545 (E)-2-Benzo[1,3]dioxol-5-yl-3-[2-cyano-5-(thiophen-3-ylmethoxy)-phenyl]-acrylic acid::CHEMBL330255

SMILES OC(=O)C(=C\c1cc(OCc2ccsc2)ccc1C#N)\c1ccc2OCOc2c1

InChI Key InChIKey=GDQDVXMTUXPLTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50065545   

TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065545((E)-2-Benzo[1,3]dioxol-5-yl-3-[2-cyano-5-(thiophen...)
Affinity DataIC50: 200nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed