BDBM50065124 CHEMBL68085::N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-phenyl]-5-fluoro-2-methyl-benzamide

SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12

InChI Key InChIKey=YAFQVGKLSDATNJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065124   

TargetVasopressin V1a receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50065124(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]AVP from vasopressin receptor (V1a) from human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50065124(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]AVP from human V2 receptor expressed in murine fibroblast cell line (LV2) membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50065124(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]AVP binding to Dawley rat hepatic vasopressin V1a receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50065124(N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [3H]AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed