BDBM50064871 CHEMBL3401273

SMILES Cc1c(NC(=O)c2cnc(nc2)C(C)(C)C)cccc1-c1cn(C)c(=O)c(Nc2ccc(cc2)C(=O)N2CCOCC2)n1

InChI Key InChIKey=NRMBZHVLFQPBAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064871   

TargetTyrosine-protein kinase BTK(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50064871(CHEMBL3401273)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50064871(CHEMBL3401273)
Affinity DataIC50: 270nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed