BDBM50064798 (3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-benzyl)-piperazine-2,5-dione::CHEMBL30034

SMILES COc1ccc(CN2[C@@H](Cc3ccccc3)C(=O)N[C@@H](CS)C2=O)cc1

InChI Key InChIKey=KIGOGXGZNGEPBS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064798   

TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of Matrix Metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of Matrix Metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50: 64nMAssay Description:Inhibition of Matrix Metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed