BDBM50064792 (3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-piperazine-2,5-dione::CHEMBL306674

SMILES SC[C@@H]1NC(=O)[C@H](CC2CCCCC2)N(CC2CCCCC2)C1=O

InChI Key InChIKey=NTWPNMLRTBRVIB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50064792   

TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of collagenase-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 121nMAssay Description:Inhibition of Matrix Metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 113nMAssay Description:Inhibition of gelatinase-B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 590nMAssay Description:Inhibition of matrilysin (Matrix metalloprotease-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of Matrix Metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of Matrix Metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed