BDBM50064789 (3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-piperazine-2,5-dione::CHEMBL71120

SMILES SC[C@H]1NC(=O)[C@@H](CC2CCCCC2)N(CC2CCCCC2)C1=O

InChI Key InChIKey=NTWPNMLRTBRVIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50064789   

TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of gelatinase-B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of collagenase-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of matrilysin (Matrix metalloprotease-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed