BDBM50064785 1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL69385

SMILES COc1ccc(cc1)N1CCN(CCC2OCCc3cc(ccc23)C(N)=O)CC1

InChI Key InChIKey=OCFFXDBBLHVFSW-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064785   

Target5-hydroxytryptamine receptor 1D(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064785(1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  8.60nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1D receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064785(1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  140nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 2A receptor from cloned Human membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064785(1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  348nMAssay Description:The compound was tested for CNS binding affinity towards Dopamine receptor D2 from cloned Human membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064785(1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  1.05E+3nMAssay Description:The compound was tested for CNS binding affinity towards Dopamine receptor D4 from cloned Human membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064785(1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  2.46E+3nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1A receptor from cloned Human membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Western lowland gorilla)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50064785(1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  5.86E+3nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1B receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed