BDBM50064645 CHEMBL3403768

SMILES CCCC(C)COc1ccc(cc1)[C@H](CO)NC(=O)[C@@H](C)c1ccccc1

InChI Key InChIKey=GXJPLTPOMVKXAT-UHFFFAOYSA-N

Data  1 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50064645   

TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataEC50:  110nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataEC50:  195nMAssay Description:Agonist activity at PPLS-HA-tagged-GPR88 (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataEC50:  194nMAssay Description:Agonist activity at PPLS-HA-tagged-GPR88 (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataEC50:  195nMAssay Description:Agonist activity at GPR88 (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataEC50:  195nMAssay Description:Agonist activity at GPR88 (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataEC50:  195nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in HEK293 cells assessed as cAMP level by GloSensor cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProbable G-protein coupled receptor 88(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064645(CHEMBL3403768)
Affinity DataKi:  612nMAssay Description:Displacement of [3H]RTI-33 from GPR88 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed