BDBM50064584 4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-4H-benzo[1,4]oxazin-3-one::CHEMBL64610

SMILES CN1C(=O)COc2cc(CCCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)ccc12

InChI Key InChIKey=WPAUYUKWTZISQN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064584   

Target5-hydroxytryptamine receptor 2A(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 620nMAssay Description:Affinity towards 5-hydroxytryptamine 2A receptor in membranes from bovine frontal cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 280nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 0.600nMAssay Description:Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 8nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 800nMAssay Description:Affinity towards 5-hydroxytryptamine 2C receptor in membranes from pig choroid plexus using [3H]N-methyl-mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064584(4-Methyl-7-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50: 30nMAssay Description:Affinity towards Alpha-1A adrenergic receptor in membranes from bovine frontal cortex using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed