BDBM50064579 6-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-3-methyl-3H-benzothiazol-2-one::CHEMBL60318

SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccc(F)cc3)cc2sc1=O

InChI Key InChIKey=CGHICUOGCBNVLX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064579   

Target5-hydroxytryptamine receptor 2A(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064579(6-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Affinity DataIC50: 200nMAssay Description:Affinity towards 5-hydroxytryptamine 2A receptor in membranes from bovine frontal cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064579(6-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Affinity DataIC50: 30nMAssay Description:Affinity towards Alpha-1A adrenergic receptor in membranes from bovine frontal cortex using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064579(6-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064579(6-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064579(6-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-3...)
Affinity DataIC50: 40nMAssay Description:Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed