BDBM50064572 3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-benzothiazol-2-one::CHEMBL64167

SMILES Cn1c2ccc(CCN3CCN(CC3)c3ccccc3)cc2sc1=O

InChI Key InChIKey=DGHMFEZDVIXRST-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064572   

Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064572(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Affinity towards 5-hydroxytryptamine 2C receptor in membranes from pig choroid plexus using [3H]N-methyl-mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064572(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Affinity DataIC50: 100nMAssay Description:Affinity towards Alpha-1A adrenergic receptor in membranes from bovine frontal cortex using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064572(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Affinity DataIC50: 200nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064572(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Affinity DataIC50: 0.700nMAssay Description:Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064572(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]racloprideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064572(3-Methyl-6-[2-(4-phenyl-piperazin-1-yl)-ethyl]-3H-...)
Affinity DataIC50: 70nMAssay Description:Affinity towards 5-hydroxytryptamine 2A receptor in membranes from bovine frontal cortex using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed