BDBM50064552 (2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL61440

SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCc3ccccc23)CC1

InChI Key InChIKey=CBLUNKVNKSMVMO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064552   

LigandPNGBDBM50064552((2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-pheny...)
Affinity DataKi:  1.70nMAssay Description:Compound was measured in vivo for its binding affinity at Alpha-1 adrenergic receptor using [3H]prazosin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50064552((2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-pheny...)
Affinity DataKi:  3.40nMAssay Description:Compound was measured in vivo for its binding affinity at 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50064552((2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-pheny...)
Affinity DataKi:  3.40nMAssay Description:Compound was evaluated for its binding affinity against 5-hydroxytryptamine 1A receptor from rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50064552((2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-pheny...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was measured in vivo for its binding affinity at Dopamine receptor D2 using [3H]spiperone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50064552((2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-pheny...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed