BDBM50064506 1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-phenyl}-1-hydroxy-urea::CHEMBL59051

SMILES CCCCN(O)C(=O)Nc1cc(cc(OC)c1OCCC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1

InChI Key InChIKey=TWOSZZZGHRJMJC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064506   

TargetPlatelet-activating factor receptor(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50064506(1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimeth...)
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]PAF from PAF receptor of human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50064506(1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimeth...)
Affinity DataIC50: 424nMAssay Description:Inhibition of 5-lipoxygenase mediated conversion of [14C]arachidonic acid to leukotrienes in RBL-2H3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50064506(1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimeth...)
Affinity DataIC50: 33nMAssay Description:In vitro affinity for human PAF receptor on platelet membranes using [3H]PAF displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50064506(1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimeth...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-2H3 (Rat basophilic leukemia) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50064506(1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimeth...)
Affinity DataIC50: 33nMAssay Description:In vitro affinity for human PAF receptor on platelet membranes using [3H]PAF displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50064506(1-Butyl-3-{3-methoxy-2-propoxy-5-[5-(3,4,5-trimeth...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-2H3 (Rat basophilic leukemia) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article