BDBM50064182 (2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-penta-2,4-dienoic acid (2,2,6,6-tetramethyl-piperidin-4-yl)-amide::CHEMBL449696

SMILES CO\C(=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1CC(C)(C)NC(C)(C)C1

InChI Key InChIKey=HEUAKNQPRZZHJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50064182   

TargetV-type proton ATPase 116 kDa subunit a 1(Chicken)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50064182((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for inhibition of V-ATPase from Chicken osteoclasts (cOc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetV-type proton ATPase 116 kDa subunit a 1(Chicken)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50064182((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...)
Affinity DataIC50: 820nMAssay Description:Compound was tested for inhibition of V-ATPase from Chicken adrenal glands(cAG)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetV-type proton ATPase subunit B, kidney isoform(Human)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50064182((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...)
Affinity DataIC50: 440nMAssay Description:Compound was tested for inhibition of V-ATPase from human kidney cortex(hK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVacuolar proton pump subunit B(Chicken)
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50064182((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...)
Affinity DataIC50: 49nMAssay Description:Compound was tested for inhibition of osteoclast vacuolar ATPase derived from chicken medullary boneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed