BDBM50064178 1-[4-(3,5-Dibromo-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL416231

SMILES [O-][n+]1ccc(CC(=O)N2CCC(CC2)C2c3ccc(Cl)cc3C=C(Br)c3cc(Br)cnc23)cc1

InChI Key InChIKey=GJOYCZXIAXQQNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064178   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50064178(1-[4-(3,5-Dibromo-8-chloro-11H-benzo[5,6]cyclohept...)
Affinity DataIC50: 40nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed