BDBM50064062 6-Chloro-4-oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-4H-chromene-8-carboxylic acid::6-chloro-4-oxo-2-(3-(2-(quinolin-2-yl)vinyl)phenyl)-4H-chromene-8-carboxylic acid::CHEMBL416769

SMILES OC(=O)c1cc(Cl)cc2c1oc(cc2=O)-c1cccc(\C=C\c2ccc3ccccc3n2)c1

InChI Key InChIKey=QIXHHLGHDFQCBP-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064062   

TargetCysteinyl leukotriene receptor 1(Guinea pig)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064062(6-chloro-4-oxo-2-(3-(2-(quinolin-2-yl)vinyl)phenyl...)
Affinity DataKd:  11nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50064062(6-chloro-4-oxo-2-(3-(2-(quinolin-2-yl)vinyl)phenyl...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed