BDBM50064019 5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride::CHEMBL553287

SMILES CC1CCN=C(N)CC1

InChI Key InChIKey=MHGPAOVGILAFJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50064019   

TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 2.40E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed