BDBM50063944 CHEMBL3402569

SMILES OCc1c(cccc1-n1ccc2cc(cc(F)c2c1=O)C1CC1)-c1ncnc2[nH]c(cc12)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key InChIKey=BAQMOLTXMVSBBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063944   

TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50063944(CHEMBL3402569)
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK (unknown origin) after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50063944(CHEMBL3402569)
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK in human Ramos cells after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed