BDBM50063792 1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclopropyl-butan-1-one::1-(8-tert-butyl-4,4-dimethylchroman-6-yl)-4-cyclopropylbutan-1-one::CHEMBL15058

SMILES CC(C)(C)c1cc(cc2c1OCCC2(C)C)C(=O)CCCC1CC1

InChI Key InChIKey=PGIRHMOXRXNJAD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063792   

TargetProstaglandin G/H synthase 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063792(1-(8-tert-Butyl-4,4-dimethyl-chroman-6-yl)-4-cyclo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed