BDBM50063740 2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-benzo[d][1,3]oxazin-4-one::CHEMBL10527

SMILES FC(F)(F)c1ccc2c(c1)nc(Nc1c(Cl)cccc1Cl)oc2=O

InChI Key InChIKey=LNIQRYXSVPXCDJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063740   

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50: 4.20E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50: 8.71E+4nMAssay Description:Concentration of compound required to inhibit 50% trypsin derived from bovine pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed