BDBM50063721 2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin-4-one::CHEMBL10065

SMILES [O-][N+](=O)c1ccc2c(c1)nc(Nc1ccccc1I)oc2=O

InChI Key InChIKey=FPVBAAYYWDYGKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063721   

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063721(2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063721(2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin...)
Affinity DataIC50: 7.80E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063721(2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration of compound required to inhibit 50% trypsin derived from bovine pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed