BDBM50063714 6-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazin-4-one::CHEMBL10246

SMILES Clc1ccc2nc(Nc3ccccc3I)oc(=O)c2c1

InChI Key InChIKey=BXNYJWKBNDSIMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063714   

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063714(6-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063714(6-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 6.25E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed