BDBM50063500 CHEMBL3398506

SMILES [#8]-[#6](=O)C(F)(F)F.[H][C@@]1([#6]-[#6]-[#6]-[#7]1-[#6]-[#6]\[#6]=[#6](/c1sccc1-[#6])-c1sccc1-[#6])[#6@@H](-[#7])-[#6](-[#8])=O

InChI Key InChIKey=YADFCMAQMRLIFS-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50063500   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063500(CHEMBL3398506)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063500(CHEMBL3398506)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063500(CHEMBL3398506)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063500(CHEMBL3398506)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063500(CHEMBL3398506)
Affinity DataKi:  1.74E+4nMAssay Description:Binding affinity to mouse GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063500(CHEMBL3398506)
Affinity DataKi:  2.04E+4nMAssay Description:Binding affinity to human GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed