BDBM50063483 5-(3,4,5-Trimethoxy-benzyl)-6,7-dihydro-5H-cyclopentapyrimidine-2,4-diamine::CHEMBL441668

SMILES COc1cc(CC2CCc3nc(N)nc(N)c23)cc(OC)c1OC

InChI Key InChIKey=MDYMIXQVIUQEDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063483   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50063483(5-(3,4,5-Trimethoxy-benzyl)-6,7-dihydro-5H-cyclope...)
Affinity DataIC50: 2.10E+4nMAssay Description:Compound was tested for inhibition activity against Toxoplasma gondii (Toxoplasma gondii) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50063483(5-(3,4,5-Trimethoxy-benzyl)-6,7-dihydro-5H-cyclope...)
Affinity DataIC50: 3.20E+4nMAssay Description:Compound was tested for inhibition activity against pneumocystis carinii (Pneumocystis carinii) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50063483(5-(3,4,5-Trimethoxy-benzyl)-6,7-dihydro-5H-cyclope...)
Affinity DataIC50: 6.90E+4nMAssay Description:Compound was tested for inhibition activity against rat liver lipophilic Dihydrofolate reductase (DHFR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed