BDBM50063401 1-[4-((R)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-4-yl-ethanone::CHEMBL291576

SMILES Clc1ccc2[C@@H](N3CCN(CC3)C(=O)Cc3ccncc3)c3ncccc3CCc2c1

InChI Key InChIKey=QIVUVRPLLRMTDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063401   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063401(1-[4-((R)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50: 490nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063401(1-[4-((R)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50: 500nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed