BDBM50063349 1-[4-(3-Bromo-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone::CHEMBL170455

SMILES Clc1ccc2C(N3CCN(CC3)C(=O)CC3CCNCC3)c3ncc(Br)cc3C=Cc2c1

InChI Key InChIKey=JPCPFEIBLZPNOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063349   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063349(1-[4-(3-Bromo-8-chloro-11H-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50: 83nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed