BDBM50063313 CHEMBL3398454

SMILES Cc1oc(nc1CCOc1ccc(C[C@@H]2CN(C[C@@H]2C(O)=O)c2nc(co2)C(F)(F)F)cc1)-c1ccccc1

InChI Key InChIKey=JMYUDUHXSWKCSZ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063313   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063313(CHEMBL3398454)
Affinity DataEC50:  1.47E+3nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063313(CHEMBL3398454)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at GAL4 tagged human PPARgamma ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063313(CHEMBL3398454)
Affinity DataIC50: 50nMAssay Description:Binding affinity to PPARgamma (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063313(CHEMBL3398454)
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PPARalpha (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed