BDBM50063303 (2R,3R,4S)-3-acetamido-4-amino-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid::(4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-trihydroxy-propyl)-5,6-dihydro-4H-pyran-2-carboxylic acid::(4S,5R,6R)-5-acetamido-4-amino-6-((1R,2R)-1,2,3-trihydroxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid::4-AMINO-2-DEOXY-2,3-DEHYDRO-N-NEURAMINIC ACID::CHEMBL52270

SMILES CC(=O)N[C@@H]1[C@@H](N)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

InChI Key InChIKey=NKENBBIXEGPQLS-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50063303   

TargetNeuraminidase(Influenza B virus (B/Lee/40))
TBA

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 410nMAssay Description:Inhibition of influenza sialidase was determined by measuring the ability to inhibit the hydrolysis of MUN by B Victoria virus grown in hen eggsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
TBA

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of influenza sialidase was determined by measuring the ability to inhibit the hydrolysis of MUN by A/Aichi virus grown in hen eggsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeuraminidase(Influenza B virus (B/Lee/40))
TBA

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of influenza B sialidase (neuraminidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
TBA

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of influenza A sialidase (neuraminidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
TBA

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 320nMAssay Description:Compound was tested for inhibitory concentration against Influenza sialidase type AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
TBA

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 410nMAssay Description:Compound was tested for inhibitory concentration against Influenza sialidase type BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSialidase-1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human neuraminidase 1 using 4MU-NANA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNeuraminidase(Vibrio cholerae)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Vibrio cholerae neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibition of human neuraminidase 4 using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human neuraminidase 3 expressed in Escherichia coli using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSialidase-2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human neuraminidase 2 expressed in Escherichia coli using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50063303((4S,5R,6R)-5-Acetylamino-4-amino-6-((1R,2R)-1,2,3-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of influenza virus neuraminidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed