BDBM50063291 CHEMBL78791::Thiophene-2-carboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide

SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1

InChI Key InChIKey=CEJURZXMIYUTSE-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50063291   

TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity determined by measuring displacement of [3H]spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  0.800nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  3.40nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  25nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  40nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(Thiophene-2-carboxylic acid {4-[2-(4-phenyl-pipera...)
Affinity DataKi:  57nMAssay Description:The binding affinity by measuring its ability to displace [3H]8-OH-DPAT radioligand in 5-hydroxytryptamine 1A receptor on rat hippocampal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed