BDBM50063047 CHEMBL3398148

SMILES C\C(=N\O)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1

InChI Key InChIKey=MSIGLHAWDSGRGI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063047   

TargetNeutrophil elastase(Human)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50063047(CHEMBL3398148)
Affinity DataIC50: 50nMAssay Description:Inhibition of human neutrophil elastase measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetNeutrophil elastase(Mouse)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50063047(CHEMBL3398148)
Affinity DataIC50: 191nMAssay Description:Inhibition of recombinant mouse neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pnitroanilide as substrate preincubated for 15 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMyeloblastin(Human)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50063047(CHEMBL3398148)
Affinity DataIC50: 220nMAssay Description:Inhibition of Pr3 (unknown origin) using t-butyloxycarbonyl-Ala-Ala-Nva-thiobenzyl ester as substrate measured for 180 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50063047(CHEMBL3398148)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine plasma thrombin using Benzoyl-Phe-Val-Arg-7-amido-4-methylcoumarin hydrochloride by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetCathepsin G(Human)
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50063047(CHEMBL3398148)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin G using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide as substrate measured for 180 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed