BDBM50062647 2-Butylamino-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-dichloro-phenyl)-amide::CHEMBL335080

SMILES CCCCNc1ncc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)C(F)(F)F

InChI Key InChIKey=PLMORJHEWFLVRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062647   

TargetCyclic AMP-dependent transcription factor ATF-1(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062647(2-Butylamino-4-trifluoromethyl-pyrimidine-5-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNuclear factor NF-kappa-B p105 subunit(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062647(2-Butylamino-4-trifluoromethyl-pyrimidine-5-carbox...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed