BDBM50062630 (S)-1-((E)-2-Cyano-3-phenyl-acryloyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide::CHEMBL335225

SMILES NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C(=C\c2ccccc2)\C#N)CC1

InChI Key InChIKey=ZPNBQEDEANVIRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50062630   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062630((S)-1-((E)-2-Cyano-3-phenyl-acryloyl)-pyrrolidine-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed