BDBM50062478 CHEMBL116641::N-Hydroxy-2-isobutyl-N'-(3-phenyl-propyl)-malonamide::N1-hydroxy-2-isobutyl-N3-(3-phenylpropyl)malonamide

SMILES CC(C)CC(C(=O)NO)C(=O)NCCCc1ccccc1

InChI Key InChIKey=XKYMHQLYNCGEBF-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062478   

TargetAminopeptidase N(Pig)
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50062478(N1-hydroxy-2-isobutyl-N3-(3-phenylpropyl)malonamid...)
Affinity DataIC50: 528nMAssay Description:Inhibition of microsomal neural aminopeptidase in pig kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50062478(N1-hydroxy-2-isobutyl-N3-(3-phenylpropyl)malonamid...)
Affinity DataIC50: 790nMAssay Description:Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50062478(N1-hydroxy-2-isobutyl-N3-(3-phenylpropyl)malonamid...)
Affinity DataKi:  537nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50062478(N1-hydroxy-2-isobutyl-N3-(3-phenylpropyl)malonamid...)
Affinity DataKi:  540nMAssay Description:Inhibition of Matrix metalloprotease-8 (Human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed