BDBM50062424 1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen-5-yl)-phenyl]-ethanone::CHEMBL320411

SMILES CC(=O)c1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key InChIKey=OMHHADZDFHTLHU-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062424   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062424(1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...)
Affinity DataIC50: 132nMAssay Description:Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062424(1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062424(1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...)
Affinity DataKi:  8.80nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed