BDBM50062403 5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL323324

SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(F)cc4)c3c12

InChI Key InChIKey=GZVGUQWAUCAVDI-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062403   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062403(5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataIC50: 342nMAssay Description:Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062403(5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  8nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062403(5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  5.30nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed