BDBM50062368 (2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4-fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane

SMILES CN1C2CCC1[C@@H](COc1ccc3OCOc3c1)[C@H](C2)c1ccc(F)cc1

InChI Key InChIKey=CUWDCKZGAWYXEX-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50062368   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 53nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 123nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 172nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 178nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 294nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 298nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 308nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 422nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 447nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.05E+3nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed